Over the past decade, Australia has experienced a troubling increase in silicosis cases, particularly among workers involved in kitchen benchtop fabrication, as well as miners and tunnel builders. Inhalation of silica dust particles can lead to lung scarring, known as silicosis, which may necessitate lung transplants or even result in premature death. Furthermore, exposure to silica dust heightens the risk of autoimmune diseases such as scleroderma and amplifies the chances of developing lung cancer. In 2023, Australia took a significant step by banning the use of engineered stone, yet despite this ban, the disease continues to claim lives, underscoring the enduring impact of this occupational hazard. The ongoing research into silicosis is of paramount importance, as it not only aids in understanding the disease better but also paves the way for improved prevention and treatment strategies.
Asbestos and Dust Diseases Research Institute (ADDRI) is an independent, not-for-profit research institute committed to reducing the impact of asbestos and dust-related diseases worldwide. We work in collaboration with individuals and organizations dedicated to eradicating these diseases while providing personalized wrap-around support to those affected by them. Our evidence-led research drives advancements in medical and scientific understanding and guides our global education and training initiatives.
We are looking to hire a Postdoctoral Research Associate with a keen interest in dust-related diseases, especially silicosis. The main focus of this position will be on exploring the mechanisms underlying silicosis development and investigating the therapeutic potential of extracellular vesicles using techniques spanning biophysical, biochemical, molecular biology, and bioinformatics. The chosen candidate will also assist with other research projects and collaborations as outlined by the Principal Scientist and Academic and Research Director.
About You:
We value integrity, respect, courage, creativity, openness, engagement, inclusion, and diversity. We are seeking to recruit individuals who share and embody these values.
Selection Criteria:
Essential:
PhD in molecular biology, cell biology, respiratory diseases, cancer research, or related field. Strong background in extracellular vesicles research. Expertise in cell biology (immortalized cells, primary cells, and ALI culture), biochemistry, and molecular biology (Western blotting, PCR, ELISA). Experience in animal model development. Experience in mass spectrometry and flow cytometry analysis. Experience in stem cell biology. Strong problem-solving, analytical skills, and strategic thinking. Proven track record of publishing research and expertise in data analysis. Exceptional communication skills (verbal and written). Ability to collaborate in multidisciplinary teams to contribute to long-term research goals. Experience in, or willingness to train, research students. Self-motivated, independent, with great attention to detail. Beneficial/Preferred:
Expertise in extracellular vesicles therapeutic potential. Experience in gene editing, CRISPR. Experience in culturing and manipulating organoid models. Experience in immunology. How to Apply:
Applications (including a cover letter, CV, two letters of reference, a brief (max. 250 words) response to all selection criteria listed above, and any additional supporting documentation) can be submitted to .
Application Process:
Shortlisting is used. Selected applicants will be invited for an interview. Once the recruitment process is completed, a final letter of rejection will be sent to the deselected applicants. Shortlisted candidates will be contacted for an online/in-person interview. Prior to the interview, you're required to submit a 2-page proposal on a given topic. During the interview, you'll also present a 15-minute overview of your previous research. Pre-employment Checks:
Your employment is conditional upon the completion of all role-required pre-employment or background checks in terms satisfactory to ADDRI. Similarly, your ongoing employment is conditional upon the satisfactory maintenance of all relevant clearances and background check requirements. If you do not meet these conditions, ADDRI may take any necessary step, including the termination of your employment.
Place of Work:
Asbestos and Dust Diseases Research Institute ( Gate 3 Hospital Road, Concord Hospital Concord NSW 2139, Australia.
The Asbestos and Dust Diseases Research Institute (ADDRI) is also known as The Asbestos Diseases Research Foundation ABN 79 121 168 867.
Ad opens: 6 January 2025.
Ad closes: 6 February 2025.
Job Type: Full-time
Pay: $85,000.00 – $95,000.00 per year
Schedule:
Monday to Friday Work Authorisation:
Australia (Required) Work Location: In person
Application Deadline: 06/02/2025
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