When Chemistry Becomes Intelligent

Nowadays, artificial intelligence (AI) and computer programs have infiltrated almost every corner of our lives; from facial recognition, language translation, image and video production, to self-driving cars and personal care aides. Other applications that might not yet be mainstream knowledge have to do with scientific exploration and research and development. For example, AI has the potential to revolutionize medical practices through augmenting medical diagnosis and have found application in drug discovery. In many places, researchers have also attempted to use AI algorithms to manipulate biology, chemistry, and physics with different setup configurations that can detect DNA modifications caused during epigenetic regulation or gene mutation, choose the most optimal reaction pathways in synthesis, and search for exotic particles using adapted learning networks.
When an oilfield's reservoir pressure is depleted during primary recovery, additional oil can be recovered by recycling the produced water and injecting it back into the reservoir. Water management is critical for such water and water-alternating-gas (WAG) floods. In its Permian basin operations, Occidental recovers, recycles, and re-injects large volumes of water for its enhanced oil recovery (EOR) operations. With real-time monitoring of oil in water (OiW) delivering reliable and continuous data, Occidental identified a way to optimize the recovery process and is working with NOV to expand the use of OiW monitoring equipment.
Petrochemicals themselves remain in short supply. This is partly because of reduced feedstock from refineries, a consequence of the pandemic-related collapse in transportation fuels demand.Global petrochemical supply is still edging back to something like normal following the US winter storms in February, during which most US capacity was shut down.A point of discussion is whether containers will become available in the right places at the right prices to relieve tightness in the European polyethylene (PE) market, once US supply has normalised. The container issue is making it difficult to move PE and polypropylene (PP) cargoes from Asia to Europe.Market intelligence from the US-based ICIS CDI team indicates that enough container freight space will be available to resume significant shipments of US PE to Europe, albeit at high prices. It will be several more weeks before domestic pipelines have been refilled, enabling US producers to refocus on exports, added CDI.
ONE OF THE GREATEST achievements of the last 30 years has been the fall in the number of people living in extreme poverty.In 1999, 1.9bn of the world's population were living on less than $1.90, the Word Bank's definition of extreme poverty. Despite setbacks caused by the pandemic, this had fallen to 698m by October 2020.Income levels alone are not enough to escape the life-threatening agony of extreme poverty. There is no point in having money if the essential goods and services to spend your money on are not available.Critical to poverty alleviation has been sufficient supply of all the things that people in the rich world take for granted. The raw materials to make the vast majority of manufactured goods include petrochemicals and polymers.Nearly all the major manufacturing chains would not have been able to function without petrochemicals.Think of medical equipment, syringes, blood bags, hospital gowns, face masks, pill bottles and medicine blister packs. None of the above could have been produced without petrochemicals.As people emerged out of extreme poverty and as economies became wealthier, modern-day medical services became more widely available.
BEFORE the pandemic, GDP growth rates in the developing world were always higher than in developed economies.And because developing economies had much lower levels of petrochemicals consumption than their rich counterparts, it meant that the multiples over GDP were higher than in the rich word, where consumption was pretty much saturated.For instance, polyethylene (PE) demand in a developed country such as Germany might have grown at 0.3% times GDP whereas in Indonesia the growth could have been one or more times higher than the rate of growth in GDP.But as The Economist wrote in this 11 July article: "In 2021 the poorest countries, which are desperately short of vaccines, are forecast to grow more slowly than rich countries for only the third time in 25 years."Might the multiples over GDP growth also be adversely affected in the developing world, trending lower than the historic norms?They will almost certainly remain higher than the rich countries. But here is the thing: as millions more people are pushed back into extreme poverty by the pandemic or are denied the opportunity to achieve middle-income status, I believe that developing-world multiples may well decline.Escaping extreme poverty means being able to, say, afford a whole bottle of shampoo for the first time rather than a single-serve sachet, thereby raising per capita polymers consumption.
GENFIT is a biopharmaceutical company focused on the discovery and development of drug candidates in areas of high unmet medical needs corresponding to a lack of suitable treatment and an increasing number of patients worldwide. GENFIT's R&D efforts are focused on bringing new medicines to market for patients with metabolic, inflammatory, autoimmune and fibrotic diseases that affect the liver (such as NASH – Nonalcoholic steatohepatitis) and more generally the gastro-intestinal arena. GENFIT's approach combines novel treatments and biomarkers.
A coalition of NGOs has sued the US EPA over an alleged lack of transparency in the TSCA new chemicals programme, which "thwart[s] the ability of the public to be informed and to provide input". According to a complaint filed by five environmental nonprofits in federal court today, the EPA has operated its TSCA premanufacture review process in a "black box, denying the public information to which they are legally entitled". Having access to timely information, they contend, is necessary to ensure the members they represent "are able to provide input on the potential risks of new chemicals and the need for protections from those risks prior to completion of EPA's reviews." And they therefore have asked the court to ensure that the EPA complies with TSCA's disclosure provisions, including by requiring that it:
The US chemical industry's trade group told President Donald Trump and state governors this week that its sector must maintain operations as the coronavirus outbreak spreads to ensure supply of chemicals needed for disinfectants, plastics for food preservation and medical equipment, and staples like diapers and soap. "The role of chemistry is particularly important today, as chemicals enable countless products that will be needed to support good hygiene and treat those who are infected with the coronavirus in the weeks and months ahead," American Chemistry Council President and CEO Chris Jahn said in a letter to Trump and governors late Tuesday. Efforts to hinder the spread of coronavirus have included cancellations of major sporting events, concerts, conferences, parades, and other large gatherings, as well as closures of bars and limiting restaurants to takeout and deliveries. Companies have increasingly sent employees to work from their homes, while hospitals, grocery stores, and drug stores work to keep up with demand for care and products.
As measures to contain the coronavirus—SARS-CoV-2—sweep across the US, the heads of privately owned chemical and instrument companies find themselves in uncharted territory trying to keep their companies going and their employees safe. C&EN reached out to CEOs of several such firms to learn what they are doing to keep business moving forward. We heard stories about setbacks, as expected supplies didn't come through, but also small triumphs, as needed safety equipment was finally found. Overall, these leaders are keeping a close eye on supplies while planning for the real possibility that orders will drop in the coming months. Keeping staff healthy and maintaining continuity in customer service are the top priorities at Boron Specialties. "We are a pretty small facility, seven people &on-site&, so as best as we can we're isolating," CEO and founder Beth Bosley says.
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