Senior Research Assistant Apply locations: Sydney Time Type: Full time Posted on: Posted 6 Days Ago Job Requisition ID: PRF7414 The primary research goal of The Developmental & Disease Epigenomics Laboratory, led by Dr Ksenia Skvortsova, is to uncover the evolution of epigenetic mechanisms governing allelic exclusion, X chromosome inactivation, and ciliogenesis, and to understand their roles in immune system development, the pathogenesis of female-biased autoimmunity, and developmental disorders with immune-related manifestations. To achieve this goal, we integrate cutting-edge single cell long read transcriptomics and epigenomics technologies, flow cytometry, chromatin modifications profiling of immune cells from animal models and clinical samples, CRISPR genome editing, as well as multi-omics bioinformatic analysis. THE OPPORTUNITY The Senior Research Assistant / Lab manager will be accountable for conducting independent experiments and overseeing daily laboratory operations (equipment and lab supplies management, safety compliance, data organisation, and team supervision) in the Developmental and Disease Epigenomics Lab, Precision Immunology Research Platform, in a collaborative framework with their supervisor Dr Ksenia Skvortsova. Salary: Up to $102,100 + 14% super + salary packaging (depending on experience) Employment Type: One year term contract with possibility for extension SNAPSHOT OF BENEFITS Generous salary packaging to save you income tax on your wages thereby boosting your monthly take home pay (max. $15,900 general expenses + $2,650 meals/accom) Ample opportunities for on-going training and development Stimulating, diverse and highly international research environment Flexible work arrangements e.g. start / finish times 18 weeks paid parental leave for both parents including paid superannuation A range of additional leave types to meet your personal needs including cultural leave, conference leave, community service and study leave Discounted Health Insurance Lifestyle discounts with our community partners WHAT YOU WILL DO Attaining previous level responsibilities as well as the following Supervisory responsibility of lab and associated activities Contributing towards research projects through to first authorship of abstracts and publications in journals specific to field Contributing to the intellectual development of grant proposals in collaboration with supervisor Supervising new staff including lab inductions and ensuring high standards and protocols are maintained ABOUT YOU Highly motivated candidate with a strong background in molecular biology, immunology and genomics. MSc or equivalent degree in Molecular Biology, Genetics, Biochemistry or a related field. Appointment at this level would normally require at least 7 years' experience within a lab, (preferably with 5 being spent at Garvan) however this alone is not sufficient Expertise in basic wet lab techniques including DNA/RNA/protein extraction, western blot, qPCR, cell culture, cell transfection. Hands-on experience with CRISPR-Cas9 technology, including guide RNA design, molecular cloning, and delivery into cells. Experience with high-parameter flow cytometry, including proficiency in using multi-colour panels with 8+ colours. Extensive experience in handling and working with laboratory mice and other model and non-model organisms. Next generation sequencing library preparation and data analysis skills (R, Python, Unix shell) are desired but not compulsory High-level analytical and critical skills Ability to maintain thorough laboratory records An interest and motivation to gain relevant research expertise Excellent organisational, written, and verbal communication skills. This is an exceptional position for persons who consistently operate at the level of a Post Doc Exercises excellent judgment – takes a 'thinking' approach to their work High level of innovativeness Goes above and beyond Consistently displays intellectual independence ABOUT GARVAN Garvan Institute of Medical Research is an independent Medical Research Institute (MRI) in Sydney, delivering scientific and clinical impact on a global basis and in partnership with organisations that share our vision. We are proud to be one of Australia's largest and most highly regarded MRI's. Our vision is global leadership in discoveries to impact and our enduring purpose is to impact human health, by harnessing information encoded in our genome. We seek to see our world-class discovery research achieve life-changing impacts, not only for individual patients with rare diseases, but for the many thousands affected by complex, common disease. Garvan promotes a diverse workplace and is committed to the principles of equity, diversity, inclusion and belonging. We are always looking for culture 'add', not culture 'fit' and are building diverse teams with great sets of complementary styles and skills to help deliver our important work effectively. HOW TO APPLY To apply for this position, please submit your application with a CV and cover letter as one document, stating why you are interested in this role. If you think you're the right person for this role, we'd love to hear how your capabilities, achievements and experience set you apart. Only applicants with full working rights in Australia are eligible to apply for this role.
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