Senior Post Doctoral Research Scientist

Senior Post Doctoral Research ScientistApply locations: NSW - Sydney, CBD, Inner West and Eastern Suburbs
Time type: Full time
Posted on: Posted Yesterday
Time left to apply: End Date: January 30, 2025 (12 days left to apply)
Job requisition id: JR140022
Job Description:Position Title: Post Doctoral Research Scientist
Employment Type: Maximum Term, Full-Time (24 months)
Hours per week: 38 hours per week plus reasonable additional hours
Position Grade: Health Managers Award Level 2
Salary: $109,857.00- $129,624.00 based salary per annum
Enterprise Agreement: The Named NSW (Non-Declared) Affiliated Health Organisations' Health Employees Agreement 2019
Department Name: St Vincent's Centre for Applied Medical Research (AMR)
About us:St Vincent's Hospital Sydney is a leading not-for-profit organisation providing health services to our community. Guided by our values of compassion, excellence, integrity and justice, we promote a culture of diversity and inclusion and empower our people to learn, grow and innovate.
Benefits of working at St Vincent's include:Generous salary packaging and Fitness Passport for eligible staffOpportunity to access a wide range of clinical and non-clinical education programsSupported post graduate opportunities within applicable fieldsCareer development opportunities across the St Vincent's Health Australia NetworkEmployee Assistance ProgramWork/Life balanceAbout the role:The Translational Immunology Program conducts research that primarily supports translation of state-of-the-art technologies to the study of immunodeficiency (primary & HIV), allergy and autoimmunity pathogenesis, diagnosis and patient monitoring at St Vincent's Hospital, Sydney. The sophisticated and multi-disciplinary approaches encompass immunology, virology and molecular biology.
The main immunological focus is on T lymphocyte biology. Lymphocyte biology work will use high dimensional flow cytometry to study T and B cells in the context of immune deficiency, both Primary immunodeficiencies and acquired immunodeficiency due to HIV infection, as well as highly immunosuppressed patients.
Assay development work will include development of novel diagnostic tests of the immune system including deep immune phenotyping using multiparameter flow cytometry, cytokine testing, cytokine autoantibody testing, immune signalling pathway testing and inflammasome pathway testing.
Studies of HIV include investigation of memory CD4 T cells as a therapy-resistant reservoir of HIV that can reignite the infection if therapy is interrupted. CD4 T cells are being isolated and cultured to show viral replication in vivo and in vitro, using a newly developed and patented PCR assay technique.
Another important aspect of CD4 T cell biology is antigen-specific memory cells, which we study using another patented flow cytometry method. This has opened up opportunities in the study of other viral infections, including the possible role of EBV in multiple sclerosis, as well as study of immune responses in TB infection.
A motivated and experienced Senior Post Doctoral Research Officer is required to conduct this research independently within the Translational Immunology Program, with strategic guidance and oversight from the Laboratory Head.
Diversity and Inclusion at St Vincent's:St Vincent's is committed to employing a workforce that reflects the community we care for. We strongly encourage applications from people that are Aboriginal and Torres Strait Islander, culturally diverse, sexuality or gender diverse and/or living with disability.
Employment with St Vincent's is subject to you having current immunity status that complies with the Occupational Assessment, Screening & Vaccination against Specified Infectious Diseases - NSW Health Policy Directive (PD2024_015) or subsequent revisions in force.
About you:We are seeking a skilled and energetic Post Doctoral Research Scientist who possesses a passion for person-centred care. We welcome applications from people who possess a PhD degree in a relevant area of science and usually have six years or more of postdoctoral research in the laboratory.
The Senior Post Doctoral Research Officer will need to have the knowledge required to lead a small team in a research group and conduct research independently. They will have deep knowledge of immunology, especially pertaining to the response to infectious agents. They will have extensive experience in the study of T lymphocytes, including immunophenotyping, cell isolations and culturing, including functional assays in vitro, and leading into nucleic acid analysis using advanced tools for amplification and sequencing.
They will demonstrate a high level of research independence and innovation and will demonstrate a significant track record of scientific achievements.
Proficiency:In addition to the range of experiences expected of an excellent scientist, they will have strong project management skills, highly developed written and verbal communication skills, ability to develop, manage and maintain internal and external working relationships, experience in managing budgets, experience in preparing and reporting on ethics applications, skills in leadership and mentoring. They will have shown an ability to meet deadlines and organize a work environment, while helping to drive and manage efficient team participation to achieve research and other project and program outcomes.
The holder of the position will bring the following expertise: use of universal precautions in handling of human blood and tissue samples; advanced flow cytometry, including complex data analysis; in vitro analysis of T cell function; extraction and purification of DNA and RNA for downstream amplification and sequencing; proven knowledge and experience of data statistics; willingness and ability to learn new skills and new disciplines as needed.
All work must be conducted in a safe, reliable, and efficient manner with a commitment to the principles of Good Laboratory Practice and in accordance with all local health and safety policies and NHMRC Code for Responsible Conduct of Research.
Application Instructions:To have your application considered you are required to upload a current CV/Resume as well as a separate cover letter/document addressing the 'Selection Criteria' as below. Internal applicants i.e. current employees of St Vincent's Hospital or an entity of SVHA are required to apply via their Workday account.
Selection Criteria:Personal integrity and demonstrated commitment to the Philosophy, Mission and Values of Mary Aikenhead Ministries and St Vincent's Health AustraliaPhD in biomedical or life sciences from a recognized tertiary organizationUnderstanding of, and demonstrated experience with achievement of, the demands, skills, techniques, and requirements listedAbility to work effectively as a member of a diverse and multidisciplinary team and to work unsupervised, directing own work and the work of different personality types, as assigned.High level conceptual, innovative, and analytic skills, particularly in the areas of project development and implementation, organizational development and management and data and ideas managementHighly developed communication, organizational and interpersonal and collaborative skills as well as stakeholder management experienceFlexibility, adaptability, agility, and responsiveness to succeed in a high demand environment with multiple changing priorities, many unknowns at any given time, and a requirement for constant learning to meet evolving and varied project and program needsAbility to write high quality journal articles, grant applications, ethics and other compliance documents, and a diverse range of reports and other documents as requiredShortlisting for this position will commence immediately. We encourage you to apply promptly as the advertisement may close early should a suitable applicant be sourced.
Applications close on 29 January 2025 Contact Details:John Zaunders 83824900, ******
Closing Date:29 January 2025 11:59pm
Reconciliation Action Plan:At St Vincent's we acknowledge the importance of creating a work environment that is welcoming, safe, equitable and inclusive for Aboriginal and/or Torres Strait Islander Employees. As part of our Commitment to Reconciliation and Closing the Gap in employment related outcomes, we encourage applications from Aboriginal and Torres Strait Islander Peoples. For further information, visit https://www.svha.org.au/about-us/reconciliation or get in contact at ****** Code of Conduct:View Code of Conduct
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