Research Assistant - Laboratory, Molecular Biology Apply locations Sydney time type Full time posted on Posted 3 Days Ago job requisition id PRF7459
The Garvan Institute of Medical Research brings together world leading researchers and clinicians, collaborating locally and globally, to improve human health. Our mission is to harness all the information encoded in our genome to better diagnose, treat, predict and prevent disease. From the individual patient with rare disease, to the many thousands affected by complex, widespread illness, we are pioneering discoveries across diseases that have the deepest impact on our community.
THE OPPORTUNITY The Swarbrick Lab are global leaders in the application of cellular genomics to human cancer, aiming to find new diagnostics and therapeutics for challenging cancers. We are a multidisciplinary team of scientists and clinicians with a vision to change cancer medicine. More information on the Swarbrick lab can be found at www.swarbricklab.com.
We are seeking an experienced research assistant to continue analysis of large and well characterised clinical cohorts of primary and metastatic cancer samples. This will include working as part of a large collaborative team to expand our extensive multi-omic studies on breast cancer, prostate cancer and melanoma, and validating the findings from these datasets.
The appointed person will have well developed skills in molecular biology, immunohistochemistry/multi-immunofluorescence, and must be comfortable working with human specimens. Previous experience with single cell technologies is desirable and an ability to troubleshoot for optimisation of new techniques/protocols is a must. The appointed person must have a willingness to work with animal models, if necessary, with previous experience desired but not essential. There will be an emphasis on designing, optimising, and executing experiments. The candidate will have high attention to detail, with extensive organisational and documentation skills, and the ability to think deeply to problem solve and take initiative in tasks. Ability to work as part of a large multi-disciplinary team and individually is a must.
Salary: Up to $105,400 + 14% superannuation + salary packaging (depending on experience) Employment Type: 1 year fixed term contract with possibility to extend to 4 years SNAPSHOT OF BENEFITS Generous salary packaging to save you income tax on your wages thereby boosting your monthly take home pay (max. $15,900 general expenses + $2,650 meals/accom)
Ample opportunities for on-going training and development
Stimulating, diverse and highly international research environment
Flexible work arrangements e.g. start / finish times
18 weeks paid parental leave for both parents including paid superannuation
A range of additional leave types to meet your personal needs including cultural leave, conference leave, community service and study leave
Discounted Health Insurance
Lifestyle discounts with our community partners
WHAT YOU WILL DO SPECIFIC ROLES REQUIRED FOR THIS POSITION (ALL LEVELS): Perform cell and tissue preparation for various next-generation sequencing analysis such as single cell RNA-seq and spatial transcriptomics
Optimise new assays for isolation of tissue products for downstream analysis, e.g. nuclei isolation
Process human tissue and bloods from research participants
Extraction, QC and clean-up of nucleic acid from tissue and blood samples
Optimise and perform immunohistochemistry and immunofluorescence assays on OCT and FFPE tissues (human and mouse)
Basic-mid level microscopy and slide imaging
Liaising with internal and external scientific service providers to prepare and submit samples
Meticulous sample tracking and cataloguing
ABOUT YOU SPECIFIC TO ALL LEVELS FOR THIS POSITION: Strong organisational and documentation skills;
Experience in molecular biology essential;
Experience with commercial nucleic extraction kits highly desirable;
Experience in IHC, IF and histology essential;
Microscopy skills and image analysis knowledge highly desirable;
Experience in cryo-sectioning desirable;
Experience working with human tissue and/or primary cell lines highly desirable;
Experience in single cell sequencing desirable;
Willingness to work with human specimens and animal models essential;
HOW TO APPLY To apply for this position, please submit your application with a CV and cover letter as one document, stating why you are interested in this role. We are reviewing applications as they are received. If you think you're the right person for this role, we'd love to hear how your capabilities, achievements and experience set you apart. Only applicants with full working rights in Australia are eligible to apply for this role.
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