Molecular Biologist – Associate Scientist/Scientist
GenEdit is a rapidly growing, early-stage company that is developing a proprietary and novel delivery platform with the potential to transform genetic medicine. Our interdisciplinary team works together across chemistry, payload design, formulation, and screening and preclinical groups to develop the next generation of gene therapies. GenEdit fosters an exciting and dynamic environment where we value impactful data and creative solutions to accelerate our progression from a platform technology to a pipeline of therapeutic candidates. We are seeking talented and motivated individuals to join our team and are expanding across all functions within the organization. Join us in South San Francisco, CA, to be at the forefront of the future of gene therapy.
Job Description
We are seeking a talented and motivated molecular biologist to join our Deep Biology team reporting to the Senior Scientist who is leading GenEdit's efforts to develop and apply DNA barcoding technologies for efficient and high throughput measurement on non-viral vector distributions across organs, tissues and cell types in small and large animals. This barcoding technology will be part of GenEdit's platform development program to screen in vivo and identify hydrophilic nanoparticles (HNP) that enable cell-specific delivery of genetic medicines. The barcode technology will allow rapid and simultaneous tracking of multiple gene vectors in one animal in vivo and allows fast discovery of tissue and cell-specific HNPs for clinical applications in gene therapy.
This is a unique opportunity to work at the intersection of genomics and therapeutics and participate in the development of transformative technology. The successful candidate will be a highly collaborative, resourceful, and effective team-player who is enthusiastic in tackling challenging complex scientific and technical problems with novel approaches and solutions. Title and salary level will be commensurate with experience and skill set.
Education and Qualifications
PhD, or MS in molecular biology, biochemistry, biomedical engineering, or a related field
1+ years of industry experience preferred
Extensive experience with molecular biology techniques, design, and generation of DNA & mRNA libraries and NGS
Experience in various mammalian and primary cell cultures, in vitro cell-based assays, and microscopy.
Knowledge and hands-on experience with CRISPR-Cas9 or nucleic acid delivery a plus
Experience in nanoparticle formulation is a plus
Some experience with using Python or other scripts for seq data analysis
Highly motivated scientist with attention to detail and the ability to independently plan, design and implement experiments
Work authorization in the US required.
Required Skills
Lab: Aid in the implementation of DNA barcode technology such as FRET assays, nucleic acid extractions from animal tissues, cell sorting, PCRs and NGS.
Study Designs: Independently design and execute experiments for further development of barcode design, mRNA libraries prep, PCR/primer design and amplification, NGS, statistical analysis.
Computational: Preferred but not required to have proficiency in bioinformatics including statistical programming language (R, python, etc.) and data science.
Collaboration and communication: Work cooperatively with peers and multidisciplinary teams, keep detailed and organized lab records, and present results at team, internal company, and external alliance meetings.
At GenEdit we are always looking to hire the absolute best talent and recognize that diversity in our experiences and backgrounds is what makes us stronger. We hire candidates of any race, color, ancestry, religion, sex, national origin, sexual orientation, gender identity, age, marital or family status, disability, veteran status, and any other status. These differences are what enable us to work towards the future we envision for ourselves, and the world.
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